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1.
World Neurosurg ; 181: e551-e561, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-37898276

RESUMO

OBJECTIVE: To present strategies for managing tumor mass formation and their corresponding postoperative outcomes. METHODS: We conducted a systematic literature review following the guidelines and protocol of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). We searched the PubMed and EMBASE databases, screened titles and abstracts, and further evaluated full-text publications to select relevant studies. Additionally, a narrative review of other pertinent articles on PubMed was performed. Case reports, cohort studies, and clinical trials were included. Animal studies were excluded. RESULTS: Of 6 patients enrolled in this study, most had American Spinal Injury Association Impairment Scale grade A (66.7%) following intramedullary injury, and 1 patient had American Spinal Injury Association Impairment Scale grade D (16.65%). The discovery time of the intramedullary mass formation ranged from approximately 5 to 14 years. Surgical intervention was performed in most cases (66.7%), with improvement reported in 3 of the surgical cases (75%). The majority of cases (83.3%) involved cervical lesions, while only 1 case (16.7%) involved a thoracic lesion. CONCLUSIONS: Due to the scarcity of described cases, there is no specific treatment for this tumor. Although our patient remained stable after conservative treatment, other studies have shown improvement in symptoms after mass resection. It is essential that the management of this complication be researched further due to the variety of clinical characteristics presented.


Assuntos
Neoplasias , Traumatismos da Medula Espinal , Traumatismos da Coluna Vertebral , Animais , Humanos , Traumatismos da Medula Espinal/etiologia , Traumatismos da Medula Espinal/cirurgia , Traumatismos da Medula Espinal/patologia , Transplante Autólogo , PubMed
2.
Arq. bras. neurocir ; 40(2): 167-173, 15/06/2021.
Artigo em Inglês | LILACS | ID: biblio-1362229

RESUMO

Introduction Cerebral metastases are the most common cancer of the central nervous system (CNS). Meningeal infiltration by neoplasms that did not originate in the CNS is a rare fact that is present in 0.02% of the autopsies. Epidemiologically, the radiological presentation mimicking a subdural hematoma is even more uncommon. We report a case of meningeal carcinomatosis by an adenocarcinoma of the prostate mimicking a chronic subdural hematoma. Case Report A 60-year-old male patient was diagnosed with prostate cancer in 2011. He underwent radical resection of the prostate, as well as adjuvant hormonal therapy and chemotherapy. Five years later, the patient presented peripheral facial paralysis that evolved with vomiting and mental confusion. Tomography and magnetic resonance imaging scans confirmed the subdural collection. At surgery, the dura was infiltrated by friable material of difficult hemostasis. The anatomicopathological examination showed atypical epithelial cells. The immunohistochemistry was positive for prostate-specific antigen (PSA) and other keymarkers, and it was conclusive for meningeal carcinomatosis by a prostate adenocarcinoma.


Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias da Próstata/complicações , Adenocarcinoma/terapia , Hematoma Subdural Crônico/terapia , Metástase Neoplásica/terapia , Próstata/cirurgia , Próstata/patologia , Adenocarcinoma/complicações , Adenocarcinoma/diagnóstico por imagem , Antígeno Prostático Específico , Hematoma Subdural Crônico/complicações
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